Pioneering Bio Science Research
Advancing Human Health Through Molecular Innovation
“Vanta Bioscience combines science, compliance, and collaboration to accelerate innovations from concept to commercialization.”
YEARS TEST FACILITY
STUDIES CONDUCTED
MAN-YEARS EXPERIENCE
DATA INTEGRITY ISSUES
DATA INTEGRITY ISSUES
Scientific Services
Discovery, Biology & Early
Pharmacology
In-vitro Pharmacology & Screening Assays-
Vanta’s assay development team has…..
Cell-Based Functional Assays-
Vanta Bioscience operates with……
Mechanism of Action (MoA) Studies-
Our scientific team works closely…
Nonclinical & IND-Enabling Toxicology
Acute Toxicity Studies-
The toxicology team has extensive….
Sub-chronic, Chronic)…..
Genetic Toxicology & Impurity Qualification
Ames Test-Vanta has conducted
the Ames test across a wide…
In-vitro Micronucleus- Applies fully
validated protocols with….
Agrochemical Toxicology & Human Risk Assessment
Ames Test-Vanta has conducted
the Ames test across a wide…
In-vitro Micronucleus- Applies fully
validated protocols with….
Ecotoxicology & Environmental Safety
Ames Test-Vanta has conducted
the Ames test across a wide…
In-vitro Micronucleus- Applies fully
validated protocols with….
INDUSTRIES
Delivering trusted, GLP-compliant research and safety solutions for industries worldwide
Pharmaceuticals & Biopharmaceuticals.
Vanta supports pharmaceutical and biopharmaceutical sponsors across the full preclinical continuum ….
Medical Devices & Combination Products
Conducts the full suite of ISO 10993-compliant biocompatibility studies — including cytotoxicity, sensitization…
Agrochemicals & Crop Protection
Supports agrochemical, crop protection, biopesticide, and plant protection product sponsors across the full….
Veterinary & Environmental Chemicals
Conducts the toxicological, residue, and environmental safety studies required to support veterinary medicinal product….
Industrial & Specialty Chemicals
Supports chemical manufacturers and importers in meeting REACH and TSCA standard information requirements….
Food, Nutraceuticals & Feed
Generates safety data for novel food ingredients, nutraceuticals, dietary supplements, and feed additives aligned….
Cosmetics & Personal Care
Vanta supports cosmetic and personal care manufacturers in substantiating ingredient and finished product safety…
Department & Facilities
Analytical Chemistry
This department handles method development, validation, and routine analysis for study types including toxicokinetics, pharmacokinetics, residue analysis, and stability testing. It is equipped with HPLC, LC-MS/MS, UV-Vis spectroscopy, and other validated instruments for complex biological and environmental samples. All methods are validated per ICH and OECD guidelines before use, with GLP-compliant data capture throughout. The team ensures concentration data underpinning exposure assessments are scientifically sound and regulatorily acceptable. With over a decade of experience, they are well-equipped for challenges like low-abundance analytes, complex matrices, and multi-residue panels.
Ecotoxicology
The Ecotoxicology department conducts regulatory studies assessing the environmental hazard and risk of chemicals, agrochemicals, and pharmaceuticals. Capabilities include aquatic toxicity testing in fish, invertebrates, and algae, and terrestrial assessments in earthworms, birds, and plants per OECD guidelines. Environmental conditions are closely controlled, and exposure concentrations are analytically verified to ensure valid dose-response data. The team has hands-on experience with ecotoxicology-specific challenges like organism acclimatization, solubility-limited exposures, and ecological endpoint interpretation. Study designs are aligned with sponsors before initiation to meet current regulatory expectations and minimize the risk of protocol deviations.
Pathology (including Clinical Chemistry)
The Pathology department provides both in-life and post-mortem assessments that form the core evidence base for toxicological evaluation. Clinical pathology covers hematology, coagulation, serum biochemistry, and urinalysis using validated automated platforms with strong attention to sample quality. Gross pathology and histopathological examinations are conducted under standardized protocols by experienced veterinary pathologists. Findings are integrated across clinical, organ weight, and histopathological data to support NOAEL determinations and risk characterization. The department’s experience with repeat-dose, carcinogenicity, and reproductive toxicology studies meets the rigorous standards expected under OECD and ICH guidelines.
Genetic Toxicology
This department performs a core genotoxicity battery per ICH S2(R1) and OECD guidelines. Key assays include the Ames test, mammalian cell genotoxicity assays, and rodent bone marrow and peripheral blood micronucleus studies, all conducted under GLP conditions. Validated test systems with characterized positive and negative control data ensure study reliability. Particular attention is given to metabolic activation, cytotoxicity, and dose selection — areas commonly flagged in regulatory reviews. The team has broad experience across pharmaceuticals, industrial chemicals, agrochemicals, and medical device extracts, including interpretation of ambiguous results.
Animal Facility
The Animal Facility supports in-life study phases with dedicated housing for rats, mice, and other rodents under controlled temperature, humidity, and light cycles, in compliance with animal welfare and GLP requirements. Separate quarantine, acclimatization, and study rooms prevent cross-contamination and protect animal welfare. Feed, bedding, and water are sourced from qualified suppliers and monitored analytically to exclude confounding contaminants. Clinical observations are recorded at defined intervals by trained personnel using standardized scoring criteria. The facility is capacity-managed to support concurrent study groups while maintaining animal welfare and study integrity even during peak utilization.
Quality Assurance
At Vanta Bioscience, the Quality Assurance Unit serves as the backbone of our GLP compliance framework, providing independent oversight of all study conduct, data integrity, and regulatory documentation. Our QA team performs systematic audits of facilities, equipment, SOPs, and in-life study phases to ensure every program meets the standards required by global regulatory authorities, including OECD, US EPA, and ICH guidelines. Study sponsors can be confident that each deliverable from Vanta has been independently reviewed and verified before release.
Engineering & Maintenance
This department ensures the operational continuity of all facility infrastructure critical to GLP study execution, including HVAC, environmental monitoring, utilities, and laboratory instrumentation. Preventive maintenance is documented per manufacturer specifications and site SOPs, with all activities logged in equipment records that form part of the GLP audit trail. A structured calibration program ensures all measurement instruments are traceable to national or international standards and recalibrated on schedule. The team also manages facility qualification activities and addresses equipment discrepancies proactively before they affect studies. This approach minimizes the risk of environmental excursions, equipment failures, or calibration lapses that could compromise data acceptability in regulatory submissions.
Information Technology (including Document Control, Test Item Control, Archives)
The IT function maintains the data infrastructure, document management systems, and electronic controls that underpin GLP compliance across Vanta. Validated LIMS and electronic data capture systems meet regulatory data integrity requirements, including audit trails, access controls, contemporaneous recording, and backup protocols. Document Control governs the full lifecycle of SOPs, protocols, amendments, and reports, ensuring only approved, current versions are in active use. Test Item Control manages receipt, storage, dispensing, and disposition of all test and reference items with full chain-of-custody documentation. The Archives function provides secure, long-term storage and retrieval of study records for audits and regulatory inspections, collectively forming the compliance backbone that supports scientific data across all departments.
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