Ecotoxicology & Environmental Safety
Fish
Conducts fish toxicity studies in GLP-compliant controlled aquatic systems using standard test species, including Oncorhynchus mykiss, Danio rerio, and Oryzias latipes, with rigorous water quality monitoring and analytical verification of test substance concentrations. Our experienced aquatic toxicology team addresses challenges posed by poorly soluble and volatile test substances.
Daphnia
Maintains healthy, well-characterized Daphnia magna cultures with documented age and generation records, ensuring test organism quality that meets guideline requirements. Our team has extensive experience conducting Daphnia studies with challenging test substances, including surfactants, mixtures, and poorly soluble agrochemicals, where standard designs require modification.
Algae
Conducts algal growth inhibition studies with Pseudokirchneriella subcapitata and Desmodesmus subspicatus as standard test species, applying validated culture systems and spectrophotometric or fluorometric growth measurement methods. Our laboratory has experience managing algaecidal test substances and conducting range-finding studies to optimize definitive test design.
Earthworm
Conducts earthworm toxicity studies in artificial OECD soil under controlled laboratory conditions. Our ecotoxicology team has extensive experience with agrochemicals that present analytical challenges in soil matrices, and applies validated extraction and bioanalytical methods to confirm actual exposure concentrations.
Birds
Conducts avian toxicity studies using standard regulatory test species, including Colinus virginianus and Anas platyrhynchos. Our team has experience with granular formulations, seed treatments, and spray application scenarios that require adapted study designs to replicate realistic environmental exposure.
Soil Microorganisms
Vanta conducts soil microbial community function studies using validated incubation protocols and enzymatic endpoint measurements. Our team is experienced in managing both highly adsorptive and biodegradable test substances, applying appropriate application methods and soil homogenization procedures to ensure uniform distribution in the test matrix.
Pollinator Safety (Bee Studies – Acute & Chronic)
Conducts acute and chronic bee studies under controlled laboratory conditions with experienced personnel trained in honeybee handling, dosing, and behavioral observation. Our team is experienced in trace-level residue analysis in sucrose solution and pollen matrices. Our expanded study portfolio allows sponsors to develop a robust pollinator risk assessment in a single, coordinated program.
Environmental Fate & Behavior
Conducts a comprehensive suite of fate and behavior studies, including hydrolysis, photolysis, soil and water metabolism, and partitioning studies, under GLP where required. Our analytical chemistry team applies validated residue methods with appropriate sensitivity and specificity for environmental matrices, ensuring that metabolite profiles and dissipation kinetics are accurately characterized.
Degradation
Conducts aerobic and anaerobic soil degradation, hydrolysis, aquatic and sediment, and photolysis studies under GLP-compliant controlled laboratory conditions. Our environmental chemistry team has extensive experience characterizing complex metabolite profiles in soil and aquatic matrices, applying mass balance verification to confirm data validity.
Mobility
Conducts soil adsorption/desorption studies and column leaching studies using a range of soil types that encompass the physicochemical variability relevant to real-world agricultural and environmental conditions. Our team supports sponsors in selecting appropriate soil types and conditions for mobility studies that reflect the intended use geography.
Persistence (Supporting Studies)
Vanta provides supporting persistence study packages tailored to the regulatory pathway, including aerobic soil metabolism studies across multiple soil types and climatic zones, aquatic metabolism studies, and sediment systems. Our team has experience designing persistence assessment programs that proactively address emerging regulatory scrutiny around metabolite persistence.
5-Batch Ecotoxicology Studies
Vanta conducts 5-batch programs using guideline-compliant aquatic and terrestrial test designs, with rigorous analytical characterization of each batch prior to and during testing. Our study directors have experience designing efficient 5-batch programs that satisfy regulatory expectations while minimizing resource use, often combining multiple endpoints within a single experimental run.