About the Role

As a Senior Scientist — Bioanalytical (LC-MS/MS), you will partner with cross-functional teams to deliver measurable impact within the Vanta Bioscience ecosystem. This role blends hands-on execution with strategic scientific oversight. You will be a key scientific contributor responsible for the development, validation, and execution of quantitative LC-MS/MS bioanalytical methods to support pharmacokinetic (PK), toxicokinetic (TK), and biomarker studies. Working in a GLP-regulated environment, you will ensure that all bioanalytical activities meet the highest standards of scientific rigor, regulatory compliance, and operational efficiency.

Responsibilities

• Method Development & Validation: Develop, optimize, and validate robust LC-MS/MS methods for the quantitative analysis of small molecules, peptides, and biomarkers in various biological matrices (plasma, serum, tissues, urine).
• Sample Analysis: Oversee and execute the analysis of study samples for GLP and non-GLP toxicology and clinical studies, ensuring timely and accurate data delivery.
• Instrumentation: Operate, maintain, and troubleshoot advanced LC-MS/MS systems (e.g., SCIEX, Waters, Agilent, Thermo Fisher) and associated software.
• Study Leadership: Act as the Bioanalytical Study Director or Principal Investigator for assigned studies. Review and approve protocols, amendments, and final bioanalytical reports.
• Compliance & Documentation: Ensure all laboratory activities comply with GLP, GCP, and applicable regulatory guidelines (FDA, EMA, OECD). Maintain accurate, contemporaneous, and complete laboratory documentation.
• Troubleshooting: Proactively identify and resolve analytical, instrumental, and matrix-related issues during method development and sample analysis.
• Mentorship & Training: Provide scientific guidance, training, and mentorship to junior scientists, research associates, and laboratory technicians to elevate team capabilities.
• Cross-functional Collaboration: Partner with Study Directors, Project Managers, and Quality Assurance (QA) teams to ensure seamless project execution and client communication.
• Continuous Improvement: Stay current with evolving regulatory bioanalytical guidelines and industry best practices, driving continuous improvement initiatives within the laboratory.

Requirements

• Education: Ph.D. in Analytical Chemistry, Pharmaceutical Sciences, Biochemistry, or a related discipline. (Candidates with an M.Pharm/M.Sc. and exceptional relevant experience will also be considered).
• Experience: 5 to 8 years of hands-on, progressive experience in a regulated bioanalytical laboratory (CRO or pharmaceutical industry) specifically working with LC-MS/MS.
• Technical Expertise: Deep understanding of sample preparation techniques (SPE, LLE, PPT, protein digestion) and chromatographic separation principles.
• Regulatory Knowledge: Strong working knowledge of GLP regulations and regulatory bioanalytical guidance documents (FDA, EMA, ICH, OECD).
• Leadership Skills: Proven track record of mentoring junior staff, managing workload distribution, and serving as a Principal Investigator/Study Director.
• Communication: Excellent written and verbal communication skills, with the ability to author complex bioanalytical reports and present data clearly to internal teams and clients.
• Problem-Solving: Strong critical thinking and troubleshooting skills with a detail-oriented approach to data integrity.

Benefits

At Vanta Bioscience, we invest in our people because they are the foundation of our scientific excellence. We offer a comprehensive benefits package designed to support your professional growth and personal well-being:

• Health & Wellness: Comprehensive medical, dental, and vision insurance coverage for you and your dependents.
• Financial Security: Competitive salary commensurate with experience, employer-provided life and accidental insurance, and retirement savings/provident fund benefits.
• Work-Life Balance: Generous paid time off (PTO), company holidays, and flexible work policies where applicable.
• Career Growth: Structured career development pathways, access to ongoing training, and opportunities to attend industry conferences.
• Work Environment: A collaborative, state-of-the-art laboratory facility in Shamirpet designed to foster innovation and scientific rigor.
• Commuter Support: Transportation assistance/facilities for easy commute to the Shamirpet campus.

Interested candidates are encouraged to apply and become a part of our mission to advance scientific research and drug development.